Serum levels of immune globulins in postmaturity

Serum immune globulins in Sjögren's syndrome.

Sj6gren's syndrome, a disease principally affecting exocrine glands but with systemic manifestations, is characterized by hypergammaglobulinaemia and the presence of a wide variety of autoantibodies. These are of several types, both organ and non-organ specific, complement-fixing, and precipitating antibodies, and in general are found in a higher proportion of patients than, for instance, in sy...

The Alleged Transformation of Serum Albumin into Serum Globulins.

Evidence for the presence of anti-Burkitt tumor globulins in pooled human immune globulins.

titers ranged from 1:80 to 1:640. Each of these 20 lots also suppressed growth of EB3 cell cultures. Complement was not required for these reactions. There was good cor relation between the immunofluorescence and growth sup pression titers. Suppression of cellular growth was related to the extent of EB virus infection in 6 human lymphoma and leukemia cell culture lines tested. The globulins re ...

Action of papain on human serum globulins.

Studies on the degradation of animal and human serum antibody type proteins by various proteolytic enzymes have indicated that molecules of approximately one-half and one-quarter the size of the parent 160,000-molecular weight protein may be readily formed (l-5). Porter (6) has recently shown that rabbit y-globulin is degraded by papain into fragments of the above size range and has separated s...

An automated estimation of serum globulins.

UTOMATIC ESTIMATION of serum globulins in human serum is normally measured as the difference between the total protein and the albumin as estimated by the dye binding capacity of the albumin, usually using 2-(4’hydroxyazobenzene) (HABA). However, it has been shown that a variety of drugs will upset dye uptake by the albumin (1). In addition, the absorbance of the native serum is so high, and th...